Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0309131
PubChem CID
Molecular Formula
C8H13N3O
Molecular Weight
167.212 g/mol
Synonyms/Alias
[161609-79-6; 4-(5-methyl-1;3;4-oxadiazol-2-yl)piperidine; 2-METHYL-5-(PIPERIDIN-4-YL)-1;3;4-OXADIAZOLE; 2-methyl-5-piperidin-4-yl-1;3;4-oxadiazole; Piperidine; 4-(5-methyl-1;3;4-oxadiazol-2-yl)-; CHE...
InChI Key
NEHQWJALQCSBBX-UHFFFAOYSA-N
InChI
InChI=1S/C8H13N3O/c1-6-10-11-8(12-6)7-2-4-9-5-3-7/h7,9H,2-5H2,1H3
IUPAC Name
2-methyl-5-piperidin-4-yl-1,3,4-oxadiazole
CAS Number
1428862-32-1

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

25 26 0 0 0 0 0 0 0 0999 V2000
4.2509 -0.4384 0.5417 C 0 0 0 0 0 0 0 0 0 0 0 0
3.0090 0.0213 -0.1415 C 0 0 0 0 0 0 0 0 0 0 0 0
2.9943 0.743...

Experimental Data

Activity Data

Target Ion Channel
Gamma-aminobutyric acid receptor subunit alpha-6
Uniprot Accession Number
Function
Agonist
Species
Rattus norvegicus (Rat)
IC50
IC50: 76000 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.3
Holding Potential
Not specified
Temperature
Room Temperature
Test Method
Binding assay
Test Species
Not specified

Binding Information

Binding Site
Extracellular domain
Binding Site Residue
GABA Binding Site

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
12
Rotatable Bonds
1
logP
0.845
Complexity
43.8797
TPSA (Ų)
50.95
H-Bond Donors
1
H-Bond Acceptors
4
Ring Count
2
New Search